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Table 2 Tight junction gene regulation in the kidney

From: Regulation of tight junction gene expression in the kidney of calbindin-D9k and/or -D28k knockout mice after consumption of a calcium- or a calcium/vitamin D-deficient diet

 

OCLN

ZO-1

CLDN1

CLDN4

CLDN5

CLDN10b

CLDN16

CLDN19

Normal

-

-

-

DKO↑

-

-

-

-

Ca2+ deficient

-

DKO↑

9 k↑, DKO↑

28 k↑, DKO↑

DKO↑

28 k↑

9 k↑, DKO↑

-

Ca2+/Vit.D deficient

-

28 k↑, DKO↑

-

28 k↑ DKO↑

28 k↑ DKO↑

28 k↑

28 k↑, DKO↑

-

  1. ↑: Significantly higher than WT mice, -: no difference, 9 k: CaBP-9 k KO mice, 28 k: CaBP-28 k KO mice, DKO: CaBP-9 k and -28 k double-KO mice.
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BMC Biochemistry

ISSN: 1471-2091

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