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Figure 3 | BMC Biochemistry

Figure 3

From: Regulation of tight junction gene expression in the kidney of calbindin-D9k and/or -D28k knockout mice after consumption of a calcium- or a calcium/vitamin D-deficient diet

Figure 3

Histologic alteration of tight junction proteins in the kidney. Immunohistochemistry was used to evaluate the differential localization of CLDN4 and 16 in the kidney. In normal conditioned mice, the renal localization of CLDN4 and 16 were compared (A). The effects of calcium deficiency on the differential localization of CLDN4 and CLDN16 were examined in the kidney of each strain of mice (B). The localization of CLDN4 and 16 was evaluated in the kidney of calcium- and vitamin D-deficient WT, CaBP-28 k KO, and DKO mice (C). Each slide was viewed at 400x magnification. Black arrows indicate immuno-positive signals.

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