Skip to main content
Figure 5 | BMC Biochemistry

Figure 5

From: Importance of extended protease substrate recognition motifs in steering BNIP-2 cleavage by human and mouse granzymes B

Figure 5

Autoradiographs showing GrB induced cleavage of wild-type human and mouse BNIP-2. In vitro transcribed and translated wild-type human and mouse BNIP-2 were incubated with varying concentrations (ranging from 3.9 nM to 1 μM (from left to right)) of human and mouse GrB. Black arrows indicate BNIP-2 precursor patterns whereas dashed and grey arrows are indicative for BNIP-2 cleavage fragments. Percentages of cleavage are shown in the progression curves of hGrB and mGrB cleavage and indicated by full and dashed lines respectively.

Back to article page

BMC Biochemistry

ISSN: 1471-2091

Contact us