Figure 4
From: Chemical-genetic induction of Malonyl-CoA decarboxylase in skeletal muscle
Acute induction of MCD does not reverse diet induced obesity or glucose intolerance. Tg-fMCDskel and control mice on HFD and LFD received 8 doses of Shield-1 (60 mg/kg) or vehicle control over two weeks. (A) Body weights were measured before and after Shield-1 treatment. (B) Mice were subjected to a GTT to determine glucose tolerance. (n = 3-10) Data are expressed as means +/- SEM.