TY - JOUR AU - Delgado, Yamixa AU - Morales-Cruz, Moraima AU - Hernández-Román, José AU - Martínez, Yashira AU - Griebenow, Kai PY - 2014 DA - 2014/08/06 TI - Chemical glycosylation of cytochrome c improves physical and chemical protein stability JO - BMC Biochemistry SP - 16 VL - 15 IS - 1 AB - Cytochrome c (Cyt c) is an apoptosis-initiating protein when released into the cytoplasm of eukaryotic cells and therefore a possible cancer drug candidate. Although proteins have been increasingly important as pharmaceutical agents, their chemical and physical instability during production, storage, and delivery remains a problem. Chemical glycosylation has been devised as a method to increase protein stability and thus enhance their long-lasting bioavailability. SN - 1471-2091 UR - https://doi.org/10.1186/1471-2091-15-16 DO - 10.1186/1471-2091-15-16 ID - Delgado2014 ER -