Species | Accession | Cluster, position | Substitution |
---|
M. barkeri
| YP_305362 | Proximal (4Fe4S)?, 1 | Cys to Asp |
G. metalloreducens
| YP_006722286 | Proximal (4Fe4S)?, 2 | Cys to Asp |
N. punctiforme
| YP_001864093 | Proximal (4Fe4S), 2 | Cys to Asn |
N. punctiforme
| YP_001864093 | Distal (4Fe4S), 1 | His to Gln |
N. punctiforme
| YP_001864093 | Medial (3Fe4S), 2 | Pro to Lys* |
D. baculatum
| YP_003157302 | Medial (4Fe4S), 2 | Pro to Cys |
- Putative FeS cluster ligating residues deviating from the standard pattern seen among two-subunit [NiFe]-hydrogenases. Each substitution is represented by multiple members; only one representative example is listed. Question marks indicate FeS cluster assignments that have not been confirmed. Asterisk (“*”) indicates a substitution not investigated in this study. The final entry represents [NiFeSe] hydrogenases, which do feature a cysteine in lieu of a proline.