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Figure 1 | BMC Biochemistry

Figure 1

From: Non-steroidal anti-inflammatory drugs activate NADPH oxidase in adipocytes and raise the H2O2 pool to prevent cAMP-stimulated protein kinase a activation and inhibit lipolysis

Figure 1

Effect of catalase and selected NSAID on Bt 2 cAMP-stimulated glycerol release in isolated rat adipocytes. Panel a, concentration-response curve for Bt2cAMP without NSAID, or plus 10–6 M of each of the NSAID indicated in the figure. Panel b, concentration-response curve for Bt2cAMP alone or in the presence of 1,000 units of catalase. Panel c, concentration-response curve for Bt2cAMP in the presence of 1,000 units of catalase without NSAID or plus 10–6 M of each of the NSAID indicated in the figure. Basal glycerol release in the absence of Bt2cAMP is indicated by an open circle. Each point represents the average ± Standard error (SE) of three to five independent experiments. *,p < 0.05 vs Bt2cAMP alone.

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BMC Biochemistry

ISSN: 1471-2091

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