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Table 1 List of partial RRMs from the BLAST search

From: Alternative splicing produces structural and functional changes in CUGBP2

Gene

Isoforms

Total RRMs

Short RRM

Lacking

Tandem

Alternative

CELF4

4

3

3rd

N-ter

RRM1-2

Isoform 1/2/3

CPEB1

3

2

2nd

C-ter

RRM1-2

-

EIF3B

1

1

1st

N-ter

-

-

EIF4B

1

1

1st

C-ter

-

-

HNRPAB

2

2

2nd

C-ter

RRM1-2

-

HNRPLL

2

3

1st

C-ter

RRM1-2

-

HTATSF1

1

2

2nd

N- & C-ter

-

-

LEMD3

2

1

1st

N-ter

-

-

LOC100132919

1

1

1st

C-ter

-

-

NONO

2

2

1st

N-ter

RRM1-2

Isoform 1

RBM10

2

2

1st

N-ter

-

Isoform 1

RBM24

2

1

1st

N-ter

-

Isoform 1/3

RBM28

2

3 (4)

1st (2nd)

C-ter

-

Isoform 1

RBM34

2

1 (2)

1st

C-ter

RRM1-2

Isoform 1

RBMS1

2

2

1st

C-ter

RRM1-2

-

RBMS2

1

2

1st

C-ter

RRM1-2

-

RBMS3

1

2

1st

C-ter

RRM1-2

-

RDM1

8

1

1st

N-ter

-

Isoform1/2/3/4

ROD1

3

4

1st

C-ter

-

-

RRP7A

1

1

1st

C-ter

-

-

SRSF1

2

2

1st

C-ter

-

-

SSB

1

2

1st

C-ter

-

-

SYNCRIP

6

3

2nd

C-ter

RRM1-3

Isoform1/2/5/6

TARDBP

1

2

2nd

C-ter

RRM1-2

-

U2AF1

3

1

1st

N-ter

-

-

U2AF2

2

3

3rd

N-ter

RRM1-2

-

UHMK1

3

1

1st

N-ter

-

Isoform 3

  1. The list shows human proteins possessing an RRM with a deleted part selected from human RefSeq proteins. In 53 human Among 457 human RRM-type proteins, 53 human RefSeq proteins (27 human genes) showed a severely disrupted RRM domain. When two RRM domains have a short linker region (less than 50 a.a), these RRMs were considered as tandem RRMs. When an alternatively spliced isoform restored the complete RRM, the name of the isoform was listed. The parentheses show RRMs that were removed form the alternatively spliced isoforms.