Figure 3

Increased expression of fibronectin in PS1−/− endothelial cells by immunostaining. Shown are primary cultures of wild type (A, B) and PS1−/− endothelial cells (C, D) immunostained for fibronectin (B, D). Panels A and C show the same fields stained for DAPI. In panel E, fluorescence intensity of fibronectin staining was measured in wild type and PS1−/− cultures. Data are presented as fluorescence intensity/unit area per number of nuclei counted which was acquired in ten random fields per culture. Asterisk indicates p < 0.05 vs. wild type (unpaired t-test). Scale bar 20 μm.