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Figure 2 | BMC Biochemistry

Figure 2

From: The role of the C8 proton of ATP in the catalysis of shikimate kinase and adenylate kinase

Figure 2

SK and AK1 sequence alignment. Sequence alignment of SK (pdb:1L4U) and AK1 (pdb:2C95) indicating the conserved amino acid residues making up the catalytic residues responsible for inducing the C8-H of ATP to be labile. The red numbering of the residues are from the second AK1 active site. Also indicated are the secondary structure motifs as predicted by the Discovery Studio® (Accelrys Inc) assignment of secondary structure motifs according to Kabsch and Sander [25] as well as that obtained from the PDB. Back ground colours indicate; Red = identical residues, green = strong similarity, blue = weak similarity and no colour = no similarity.

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