Figure 3
Temperature and pH effects on the activities of recombinant canine and human TK1. The activities of dog (A) and human (B) TK1 were measured using [3 H]-AZT as a substrate at different temperatures. The activities of canine (C) and human (D) TK1 were measured with AZT as substrate at different pH (indicated on the x-axis) and different temperatures: 37 °C (filled bars) and 45 °C (open bars).