Homology based modeling of SSB
. (a) Model of the SSBEC derived from the crystal structure of a chymotrypsin truncated SSBEC monomer lacking 42 C-terminal residues (PDB ID 1QVC). (b) Model of the SSBBA derived from the crystal structure SSBEC monomer (PDB ID 1QVC). Both of these structures were generated using PyMol. In SSBEC, Trp55, Trp89, and Phe61 are important in the ssDNA binding, which are replaced by Phe47, Tyr82, and Trp53 respectively in SSBBA. Most notably, His56 residue of SSBEC, required for monomer-monomer interaction is replaced by Ile48 in SSBBA.