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Table 2 Ratios of transfected R and C subunits

From: Protein kinase A type I activates a CRE-element more efficiently than protein kinase A type II regardless of C subunit isoform

PKA subunits

[R]*

[C]

R/C ratio

Holoenzyme

   

PKAI

22 ± 1.5

25 ± 1.4

0.88

PKAII

23 ± 1.5

24 ± 2.9

0.96

  1. * Concentration of R and C subunit (pmol/mg protein) were determined at saturating concentrations of cAMP and assuming two cAMP binding sites per R subunit and 600 pmol phosphate transferred by pure bovine C per min per mg [65].