Figure 5
Time course of 53BP1 relocalization following SRC3 knockdown. (A) HeLa cells were transfected with control siRNA, or siRNA targeting SRC3. After 72 hr, the cells were stimulated with etoposide for 30 minutes, washed and then fixed and examined at various time points for 53BP1-dependent foci formation. (B)Plot of the average number of foci/cell at a given time point following etopiside treatment.