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Figure 6 | BMC Biochemistry

Figure 6

From: SUMO-1 regulates the conformational dynamics of Thymine-DNA Glycosylase regulatory domain and competes with its DNA binding activity

Figure 6

Glycosylase kinetics of TDG and sumoylated TDG proteins in absence and presence of free SUMO-1 or BSA on G:U and G:T repair in NMR buffer. (A, B) G:U repair activity was measured for TDG (A) or sumoylated TDG (B) in the presence or absence of five equimolar amounts of free SUMO-1 or BSA at pH 6.6. (C) G:T repair activity of sumoylated TDG in the presence or absence of five equimolar amounts of free SUMO-1 or BSA at pH 6.6.

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