Putative cis -acting elements of the 5'-flanking region of the human fibin gene. Grey boxes indicate the transcription consensus-binding sequences of glucocorticoid-responsive and -related elements (GRE), cAMP responsive elements (CRE), LEF/TCF, NF-κB, AP-1, Nrf2 and TATA binding protein (TATA) factors. EST alignments (see Additional file 1, Figure S1) indicated more than one transcriptional start site (TSP). TSP indicates the most frequently 5'-end of ESTs. The translation start codon is underlined.