From: A novel method for screening the glutathione transferase inhibitors
Inhibitor (1 μM) | Specific GST activity (units/mg) | |
---|---|---|
CDNB (1 mM) | DCNB (1 mM) | |
Control | 2.80 ± 0.01 (100%) | 4.51 ± 0.02 (100%) |
F1 | 1.20 ± 0.01(43.1%) | 2.65 ± 0.02 (58.8) |
F2 | 0.73 ± 0.01 (26.1%) | 1.49 ± 0.02 (33.2%) |
tannic acid | 0.16 ± 0.01 (5.6%) | 0.49 ± 0.01 (10.9%) |
cibacron blue | 0.51 ± 0.01 (18.3%) | 0.96 ± 0.01 (21.3%) |
hematin | 0.99 ± 0.01 (35.2%) | 1.90 ± 0.02 (42.1%) |
ethacrynic acid | 1.54 ± 0.01 (55.1%) | 3.66 ± 0.02 (81.2%) |