Identification of four novel phosphorylation sites in estrogen receptor α: impact on receptor-dependent gene expression and phosphorylation by protein kinase CK2

Table 2 Consensus kinase recognition sequences for novel ERα phosphorylation sites

Phosphorylation site	Sequence	Consensus recognition site	Putative Kinase
Serine 47	YLD-( S ) - *(S)K* - PAV	(S/T)-X-R/K	PKC? (imperfect)
Serine 282	GEVG- *(S)AGD-* M	(S/T)-X-X-E/D	CK2
Serine 294	NLWP- *(S)P* - LMI	(S/T)-P	Proline-directed kinase
Serine 559	RGGA- *(S)VEE* - T	(S/T)-X-X-E/D	CK2

ISSN: 1471-2091