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Figure 5 | BMC Biochemistry

Figure 5

From: TIPT2 and geminin interact with basal transcription factors to synergize in transcriptional regulation

Figure 5

Binding and activation of the NF1 promoter by TIPT2 and TBPL1. (A) TIPT2 (120–240 ng) and TBPL1-TFIIA (20 ng) binding to the NF1 oligonucleotide. Geminin (120 ng) binding to the NF1 oligonucleotides. (B) Activation of the NF1 promoter by the indicated combinations of TIPT2, TBPL1 and geminin. (C) Activation of the NF1 promoter by the indicated combinations of TIPT2, TBPL1 and geminin in the presence of siRNA against geminin.

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BMC Biochemistry

ISSN: 1471-2091

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