Figure 11
From: A novel human NatA Nα-terminal acetyltransferase complex: hNaa16p-hNaa10p (hNat2-hArd1)
Knockdown of h NAA16 induces cell death. HeLa cells were transfected with 50 nM unspecific, hNAA15 or hNAA16 siRNAs. Cells were analyzed by TUNEL-assay 72 hours post transfection. In the left column, Hoechst33342 staining visualizes nuclei in blue; in the middle column, TMR-red TUNEL staining visualizes DNA breaks in red; in the right column, Hoechst and TUNEL signals are merged. Neg: negative controls omitting active TUNEL-reaction enzyme.