Sort by
Previous Page Page 2 of 22 Next Page
  1. Research article

    The GH5 1,4-β-mannanase from Bifidobacterium animalis subsp. lactis Bl-04 possesses a low-affinity mannan-binding module and highlights the diversity of mannanolytic enzymes

    β-Mannans are abundant and diverse plant structural and storage polysaccharides. Certain human gut microbiota members including health-promoting Bifidobacterium spp. catabolize dietary mannans. Little insight is ...

    Johan Morrill, Evelina Kulcinskaja, Anna Maria Sulewska, Sampo Lahtinen, Henrik Stålbrand, Birte Svensson and Maher Abou Hachem

    BMC Biochemistry 2015 16:26

    Published on: 11 November 2015

  2. Research article

    The eukaryotic translation initiation factor 3f (eIF3f) interacts physically with the alpha 1B-adrenergic receptor and stimulates adrenoceptor activity

    eIF3f is a multifunctional protein capable of interacting with proteins involved in different cellular processes, such as protein synthesis, DNA repair, and viral mRNA edition. In human cells, eIF3f is related...

    Mario Javier Gutiérrez-Fernández, Ana Edith Higareda-Mendoza, César Adrián Gómez-Correa and Marco Aurelio Pardo-Galván

    BMC Biochemistry 2015 16:25

    Published on: 23 October 2015

  3. Research article

    Evaluating the role of a trypsin inhibitor from soap nut (Sapindus trifoliatus L. Var. Emarginatus) seeds against larval gut proteases, its purification and characterization

    The defensive capacities of plant protease Inhibitors (PI) rely on inhibition of proteases in insect guts or those secreted by microorganisms; and also prevent uncontrolled proteolysis and offer protection aga...

    V D Sirisha Gandreddi, Vijaya Rachel Kappala, Kunal Zaveri and Kiranmayi Patnala

    BMC Biochemistry 2015 16:23

    Published on: 22 October 2015

  4. Research article

    Respiration and substrate transport rates as well as reactive oxygen species production distinguish mitochondria from brain and liver

    Aberrant mitochondrial function, including excessive reactive oxygen species (ROS) production, has been implicated in the pathogenesis of human diseases. The use of mitochondrial inhibitors to ascertain the si...

    Aaron M. Gusdon, Gabriel A. Fernandez-Bueno, Stephanie Wohlgemuth, Jenelle Fernandez, Jing Chen and Clayton E. Mathews

    BMC Biochemistry 2015 16:22

    Published on: 10 September 2015

  5. Research article

    Purification and characterization of a cytochrome c with novel caspase-3 activation activity from the pathogenic fungus Rhizopus arrhizus

    Members of Rhizopus species are the most common cause of mucormycosis, a rare but often fatal fungal infection. Host induced pathogen apoptosis and pathogen induced host cell apoptosis are often involved in funga...

    Manoj Saxena, Rohit Kumar Sharma, Josell Ramirez-Paz, Arthur D. Tinoco and Kai Griebenow

    BMC Biochemistry 2015 16:21

    Published on: 3 September 2015

    The Erratum to this article has been published in BMC Biochemistry 2016 17:3

  6. Research article

    Complex kinetics and residual structure in the thermal unfolding of yeast triosephosphate isomerase

    Saccharomyces cerevisiae triosephosphate isomerase (yTIM) is a dimeric protein that shows noncoincident unfolding and refolding transitions (hysteresis) in temperature scans, a phenome...

    Ariana Labastida-Polito, Georgina Garza-Ramos, Menandro Camarillo-Cadena, Rafael A. Zubillaga and Andrés Hernández-Arana

    BMC Biochemistry 2015 16:20

    Published on: 3 September 2015

  7. Research article

    Identification of inhibitors that target dual-specificity phosphatase 5 provide new insights into the binding requirements for the two phosphate pockets

    Dual-specificity phosphatase-5 (DUSP5) plays a central role in vascular development and disease. We present a p-nitrophenol phosphate (pNPP) based enzymatic assay to screen for inhibitors of the phosphatase domai...

    Terrence S. Neumann, Elise A. Span, Kelsey S. Kalous, Robert Bongard, Adam Gastonguay, Michael A. Lepley, Raman G. Kutty, Jaladhi Nayak, Chris Bohl, Rachel G. Lange, Majher I. Sarker, Marat R. Talipov, Rajendra Rathore, Ramani Ramchandran and Daniel S. Sem

    BMC Biochemistry 2015 16:19

    Published on: 19 August 2015

  8. Research article

    Design of symmetric TIM barrel proteins from first principles

    Computational protein design is a rapidly maturing field within structural biology, with the goal of designing proteins with custom structures and functions. Such proteins could find widespread medical and ind...

    Deepesh Nagarajan, Geeta Deka and Megha Rao

    BMC Biochemistry 2015 16:18

    Published on: 12 August 2015

  9. Research article

    Kv1.3 contains an alternative C-terminal ER exit motif and is recruited into COPII vesicles by Sec24a

    Potassium channels play a fundamental role in resetting the resting membrane potential of excitable cells. Determining the intracellular trafficking and localization mechanisms of potassium channels provides a...

    John M. Spear, Dolly Al Koborssy, Austin B. Schwartz, Adam J. Johnson, Anjon Audhya, Debra A. Fadool and Scott M. Stagg

    BMC Biochemistry 2015 16:16

    Published on: 10 July 2015

  10. Research article

    Human POLD1 modulates cell cycle progression and DNA damage repair

    The activity of eukaryotic DNA polymerase delta (Pol δ) plays an essential role in genome stability through its effects on DNA replication and repair. The p125 catalytic subunit of Pol δ is encoded by POLD1 gene ...

    Jing Song, Ping Hong, Chengeng Liu, Yueqi Zhang, Jinling Wang and Peichang Wang

    BMC Biochemistry 2015 16:14

    Published on: 19 June 2015

  11. Research article

    Sigma-1 receptor directly interacts with Rac1-GTPase in the brain mitochondria

    Small Rho-GTPases are critical mediators of neuronal plasticity and are involved in the pathogenesis of several psychiatric and neurological disorders. Rac-GTPase forms a multiprotein complex with upstream and...

    Nino Natsvlishvili, Nino Goguadze, Elene Zhuravliova and David Mikeladze

    BMC Biochemistry 2015 16:11

    Published on: 30 April 2015

  12. Research article

    Nickel quercetinase, a “promiscuous” metalloenzyme: metal incorporation and metal ligand substitution studies

    Quercetinases are metal-dependent dioxygenases of the cupin superfamily. While fungal quercetinases are copper proteins, recombinant Streptomyces quercetinase (QueD) was previously described to be capable of inco...

    Dimitrios Nianios, Sven Thierbach, Lenz Steimer, Pavel Lulchev, Dagmar Klostermeier and Susanne Fetzner

    BMC Biochemistry 2015 16:10

    Published on: 23 April 2015

  13. Methodology article

    Comparative metabolic fingerprinting of Gentiana rhodantha from different geographical origins using LC-UV-MS/MS and multivariate statistical analysis

    Gentiana rhodantha, a rich source of iridoids and polyphenols, is a traditional ethnomedicine widely used in China. Metabolic fingerprinting based on a LC-UV-MS/MS method was applied to explore...

    Yu Pan, Ji Zhang, Tao Shen, Yan-Li Zhao, Yuan-Zhong Wang and Wan-Yi Li

    BMC Biochemistry 2015 16:9

    Published on: 28 March 2015

  14. Reviewer acknowledgement

    BMC Biochemistry reviewer acknowledgement, 2014

    The editors of BMC Biochemistry would like to thank all our reviewers who have contributed their time to the journal in Volume 15 (2014).

    Guangde Tu

    BMC Biochemistry 2015 16:7

    Published on: 17 February 2015

  15. Research article

    The exchanged EF-hands in calmodulin and troponin C chimeras impair the Ca2+-induced hydrophobicity and alter the interaction with Orai1: a spectroscopic, thermodynamic and kinetic study

    Calmodulin (CaM) plays an important role in Ca2+-dependent signal transduction. Ca2+ binding to CaM triggers a conformational change, forming a hydrophobic patch that is important for target protein recognition. ...

    Drake Jensen, Nicole Reynolds, Ya-Ping Yang, Shubha Shakya, Zhi-Qiang Wang, Dennis J Stuehr and Chin-Chuan Wei

    BMC Biochemistry 2015 16:6

    Published on: 15 February 2015

  16. Research article

    Identification of fragments from Autographa Californica polyhedrin protein essential for self-aggregation and exogenous protein incorporation

    Baculoviruses are widely used for the production of recombinant proteins, biopesticides and as gene delivery systems. One of the viral forms called polyhedra has been recently exploited as a scaffold system to...

    Alicia Sampieri, Agustín Luz-Madrigal, Jesus Zepeda and Luis Vaca

    BMC Biochemistry 2015 16:5

    Published on: 4 February 2015

  17. Research article

    Digested wheat gluten inhibits binding between leptin and its receptor

    Leptin resistance is considered a primary risk factor for obesity. It has been hypothesized that dietary cereal grain protein could cause leptin resistance by preventing leptin from binding to its receptor. No...

    Tommy Jönsson, Ashfaque A Memon, Kristina Sundquist, Jan Sundquist, Stefan Olsson, Amarnadh Nalla, Mikael Bauer and Sara Linse

    BMC Biochemistry 2015 16:3

    Published on: 20 January 2015

  18. Research article

    Histone deacetylase inhibitor sodium butyrate suppresses DNA double strand break repair induced by etoposide more effectively in MCF-7 cells than in HEK293 cells

    Histone deacetylase inhibitors (HDACi’s) are emerging as promising anticancer drugs alone or in combination with chemotherapy or radiotherapy agents. Previous research suggests that HDACi’s have a high degree ...

    Liping Li, Youxiang Sun, Jiangqin Liu, Xiaodan Wu, Lijun Chen, Li Ma and Pengfei Wu

    BMC Biochemistry 2015 16:2

    Published on: 16 January 2015

Previous Page Page 2 of 22 Next Page