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Figure 9 | BMC Biochemistry

Figure 9

From: Nuclear annexin II negatively regulates growth of LNCaP cells and substitution of ser 11 and 25 to glu prevents nucleo-cytoplasmic shuttling of annexin II

Figure 9

Site-directed change of ser11 and ser25 to glutamic acid prevents nuclear entry of annexin II. GFP-fused annexin II containing Ser to Ala or Ser to Glu either singly or in combination were generated as described in materials and methods. Transient transfection of LNCaP cells was performed followed by treatment with or without LMB. Confocal microscopic observations were made and representative images are shown. Bar: 10 μm.

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BMC Biochemistry

ISSN: 1471-2091

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