Figure 1
From: The intein of the Thermoplasma A-ATPase A subunit: Structure, evolution and expression in E. coli
Alignment of archaeal ATPase A-subunit intein sequences. The large gap in the Thermoplasma sequences indicates that the Thermoplasma acidophilum (Tac) and Thermoplasma volcanium (Tvo) inteins do not contain an endonuclease domain and only consist only of the self splicing domain, while the Pyrococcus abyssi (Pab), P. furiosus (Pfu) and P. horikoshii (Pho) A-ATPase A-subunits inteins are bifunctional. Regions corresponding to conserved blocks [18] are indicated in bold and labeled A-H. Blocks A, B, F and G are part of the splicing domain, whereas blocks C, D, E, H are typical for endonucleases of the LAGDIDAG type [18].