Table 1 Changes in migration-related genes in both IMR90 RSH and IMR90 hTERT cells
Gene symbol | Gene name | Function on cell migration | Fold change | |
|---|---|---|---|---|
IMR90 RSH vs control | IMR hTERT vs control | |||
IL6 | Interleukin 6 | Positive regulation of cell migration | 14.135 | 2.665 |
APOE | Apolipoprotein E | Negative regulation of cell motion | 7.82747 | 5.968 |
COX-2 | Cyclooxygenase-2 | Positive regulation of cell migration | 6.094 | 2.475 |
LAMA5 | Laminin, alpha 5 | Positive regulation of cell migration | 4.273 | 2.498 |
IL8 | Interleukin 8 | Positive regulation of locomotion | 3.755 | 2.588 |
BTG1 | B-cell translocation gene 1 | Positive regulation of cell migration | 3.34 | 3.392 |
SCG2 | Secretogranin II | Positive regulation of locomotion | 3.051 | 3.563 |
ETV4 | Ets variant 4 | Positive regulation of cell migration | 3.047 | 2.884 |
CKLF | Chemokine-like factor | Positive regulation of cell migration | 2.865 | 3.246 |
COL18A1 | Collagen, type XVIII, alpha 1 | Positive regulation of cell migration | 2.738 | 4.533 |
LAMA1 | Laminin, alpha 1 | Positive regulation of cell migration | 2.631 | 6.232 |
LAMA4 | Laminin, alpha 4 | Positive regulation of cell migration | 2.582 | 2.3 |
MYH10 | Myosin, heavy chain 10, non-muscle | Positive regulation of cell migration | 2.495 | 5.678 |
BBS2 | Bardet-Biedl syndrome 2 | Positive regulation of cell migration | 2.479 | 2.415 |
WASF2 | WAS protein family, member 2 | Positive regulation of cell migration | 2.421 | 5.506 |
TWIST1 | Twist homolog 1 (Drosophila) | Positive regulation of cell migration | 2.409 | 3.328 |
NR4A2 | Nuclear receptor subfamily 4, A2 | Positive regulation of cell migration | 2.398 | 3.488 |
SMAD3 | SMAD family member 3 | Positive regulation of cell migration | 2.396 | 3.602 |
PLAT | Plasminogen activator, tissue | Positive regulation of cell migration | 2.367 | 3.977 |
SEMA3F | Semaphorin 3Â F | Positive regulation of cell migration | 2.348 | 5.71 |
NUP85 | Nucleoporin 85Â kDa | Positive regulation of cell migration | 2.214 | 3.579 |
PALM | Paralemmin | Positive regulation of cell migration | 2.151 | 2.42 |
ROBO3 | Roundabout, axon guidance receptor, homolog 3 | Positive regulation of cell migration | 2.116 | 2.929 |
NDE1 | nudE nuclear distribution gene E homolog 1 | Positive regulation of cell migration | 2.115 | 2.388 |
CDKN1B | Cyclin-dependent kinase inhibitor 1B | Negative regulation of cell motion | 2.068 | 2.316 |
LYN | v-yes-1 Yamaguchi sarcoma oncogene | Positive regulation of cell motion | 2.032 | 4.017 |
PRKDC | Protein kinase, DNA-activated, catalytic polypeptide | Positive regulation of cell migration | 2.024 | 3.337 |
ACTG1 | Actin, gamma 1 | Positive regulation of cell migration | -5.041 | -3.107 |