Figure 2

Alignment of typical motifs of DGAT1 (a) and DGAT2 (b) families. Figure 2a shows the alignment of the FYxDWWN motif which is a potential acyl-CoA binding motif in proteins of the DGAT1 family [44]. Figure 2b represents the partially modified HPHG motif representing a potential part of the active site in DGAT2 family proteins [45]. NCBI accession numbers of reference proteins: HsDGAT1 [Homo sapiens, NP_036211.2], HsACAT1 [H. sapiens, NP_003092.4], HsACAT2 [H. sapiens, NP_003569.1], HsDGAT2 [H. sapiens, NP_115953.2], HsAWAT1 [H. sapiens, NP_001013597.1], HsAWAT2 [H. sapiens, NP_001002254.1].