Figure 4From: The role of the C8 proton of ATP in the catalysis of shikimate kinase and adenylate kinaseShikimate kinase KIE of WT and T17I mutant enzymes. The effect of the concentration of ATP and C8D-ATP on the KIE of M. tuberculosis shikimate kinase. ▲ = WT KIE, (green triangle) = T17I KIED, (blue inverted triangle) = WT KIED, (red inverted triangle) = T17 KIE.Back to article page