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Figure 4 | BMC Biochemistry

Figure 4

From: Computational identification and experimental characterization of substrate binding determinants of nucleotide pyrophosphatase/phosphodiesterase 7

Figure 4

Comparison of hNPP7 models based on three different template structures. Green ribbons represent hNPP7 residues aligned against residues in the template. Magenta ribbons represent hNPP7 residues aligned against gaps in the template. Zn2+ ions are shown as blue spheres and the position of N146 is shown as a spacefilling model. A. hNPP7 based on PDB entry 2GSO[16] (Xac. NPP), 24.7% amino acid identity. B. hNPP7 based on PDB entry 2XR9[5] (Rat NPP2), 24.9% amino acid identity. C. hNPP7 based on PDB entry 3NKM[6] (Mouse NPP2), 25.3% amino acid identity.

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BMC Biochemistry

ISSN: 1471-2091

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