Figure 2
From: Delineation of the Pasteurellaceae-specific GbpA-family of glutathione-binding proteins
Cut-and-spliced version of a hierarchical clustering-based multiple sequence alignment of the top-100 GbpA homologs found in the NCBI microbial protein database reveal invariant signature sequences for the GbpA and DppA subfamily. Green-boxed residues of GbpA family members are ligand-interacting residues identified from the GSSG/GbpAHp complex crystal structure (pdb id. 3M8U). Purple-boxed residues of DppA family members interact with the dipeptide allocrite in the E. coli DppA/glycylleucine complex structure (pdb id. 1DPP). Sequence names are NCBI Reference Sequence identifiers. The numbering on the top corresponds to the GbpAHp sequence, while the numbering at the bottom refers to the DppA sequence of E. coli.