Figure 5From: Identification of inhibitors of Plasmodium falciparum phosphoethanolamine methyltransferase using an enzyme-coupled transmethylation assayEffect of HNMT inhibitors and antimalarial aminoquinolines and amino alcohols on PfPMT activity. (A) Effect of the HNMT inhibitors SKF91488 (SKF), tacrine (Tac), diphenhydramine (Dip) and chlorpromazine (Chl) on PfPMT activity. (B) Effect of chloroquine (CQ), quinacrine (QC), quinidine (QD) and quinine (QN) on PfPMT activity. The data are the means +/- S.D. for three independent experiments.Back to article page