Table 1 Relative percent abundance (RPA) data for the mass spectra in Figures 1 and 4
Figure 1a -- Albumin | ||||||||
|---|---|---|---|---|---|---|---|---|
m/z 66438 | m/z 66470 | m/z 66557 | m/z 66600 & 66614 | m/z 66655 | m/z 66719 | m/z 66818 | Sample Treatment | |
RPA Native | RPA SO2H | RPA S-Cys | RPA Native Glycated & S-CysGly | RPA NonCov. Phosphate Adduct | RPA S-Cys + Glycation | RPA CPPCHD Adduct | H2O2 | CPPCHD |
32% | 10% | 38% | 6% | 3% | 5% | 6% | + | + |
51% | 0% | 34% | 9% | 1% | 5% | 0% | - | + |
32% | 12% | 43% | 6% | 3% | 4% | 0% | + | - |
49% | 0% | 36% | 6% | 3% | 5% | 0% | - | - |
Figure 1b -- TTR | ||||||||
m/z 13761 | m/z 13793 | m/z 13880 | m/z 13937 | m/z 14067 | m/z 14141 | Â | Sample Treatment | |
RPA Native | RPA SO2H | RPA S-Cys | RPA S-CysGly | RPA S-Glutathione | RPA CPPCHD Adduct | Â | H2O2 | CPPCHD |
23% | 9% | 48% | 13% | 3% | 3% | Â | + | + |
39% | 3% | 46% | 10% | 3% | 0% | Â | - | + |
21% | 12% | 52% | 12% | 3% | 0% | Â | + | - |
39% | 2% | 48% | 10% | 1% | 0% | Â | - | - |
Figure 4a -- Albumin | ||||||||
m/z 66438 | m/z 66470 | m/z 66557 | m/z 66600 & 66614 | m/z 66636 | m/z 66655 | m/z 66719 | Sample Treatment | |
RPA Native | RPA SO2H | RPA S-Cys | RPA Native Glycated & S-CysGly | RPA TNB Adduct | RPA NonCov. Phosphate Adduct | RPA S-Cys + Glycation | H2O2 | TNB |
32% | 7% | 37% | 3% | 15% | 3% | 4% | + | + |
49% | 0% | 37% | 5% | 0% | 4% | 5% | - | + |
32% | 13% | 42% | 5% | 0% | 3% | 4% | + | - |
48% | 0% | 38% | 7% | 0% | 3% | 4% | - | - |
Figure 4b -- TTR | ||||||||
m/z 13761 | m/z 13793 | m/z 13880 | m/z 13937 | m/z 13959 | m/z 14067 | Â | Sample Treatment | |
RPA Native | RPA SO2H | RPA S-Cys | RPA S-CysGly | RPA TNB Adduct | RPA S-Glutathione | Â | H2O2 | TNB |
19% | 11% | 48% | 11% | 7% | 4% | Â | + | + |
29% | IP | 50% | 9% | 8% | 4% | Â | - | + |
21% | 12% | 52% | 12% | 0% | 3% | Â | + | - |
38% | 2% | 46% | 12% | 0% | 2% | Â | - | - |